1 Variant maps to more than 3 different locations 2 None of the variant alleles match the reference allele 3 Variant has more than 3 different alleles 4 Loci with no observed variant alleles in dbSNP 5 Variant does not map to the genome 6 Variant has no genotypes 7 Genotype frequencies do not add up to 1 8 Variant has no associated sequence 9 Variant submission has been withdrawn by the 1000 genomes project due to high false positive rate 11 Additional submitted allele data from dbSNP does not agree with the dbSNP refSNP alleles 12 Variant has more than 3 different submitted alleles 13 Alleles contain non-nucleotide characters 14 Alleles contain ambiguity codes 15 Mapped position is not compatible with reported alleles 16 Flagged as suspect by dbSNP 17 Variant can not be re-mapped to the current assembly 18 Supporting evidence can not be re-mapped to the current assembly 19 Variant maps to more than one genomic location 20 Variant at first base in sequence 21 Reference allele does not match the bases at this genome location 22 Alleles cannot be resolved